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HIV damages the immune system, interfering with the body's ability to fight infections.
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Nelvir 250mg
Nelvir (Nelfinavir Mesylate 250mg Tablets) (Nelvir )

What is Nelvir?

Nelvir contains Nelfinavir Mesylate, an antiretroviral medication used to treat HIV infection. It belongs to the protease inhibitor (PI) class, working by blocking the replication of the HIV virus in the body. Nelvir is typically used as part of combination therapy to manage HIV and improve immune function.


How to Use Nelvir

  • Dosage: Follow your doctor’s prescription. Nelvir is usually taken 2-3 times daily with food.
  • Instructions: Swallow the tablets whole with water. Maintain a consistent schedule to optimize effectiveness.

Contraindications

Do not use if:

  • Allergic to Nelfinavir Mesylate or any ingredient in the tablet.
  • Taking medications such as rifampin, St. John’s Wort, or ergot derivatives, as these can interact with Nelvir.

Side Effects

Common Side Effects:

  • Diarrhea
  • Nausea
  • Stomach pain
  • Fatigue

Serious Side Effects (Seek Help):

  • Severe allergic reactions (rash, swelling, difficulty breathing)
  • Persistent vomiting or severe abdominal pain
  • Unexplained bruising or bleeding

Precautions

  • Inform your doctor if you have liver disease, diabetes, or high cholesterol.
  • Avoid missing doses, as irregular use can reduce the drug's effectiveness.
  • Nelvir does not cure HIV or prevent its transmission. Use appropriate precautions to prevent spreading the virus.

Drug Interactions

  • Avoid combining Nelvir with certain medications like rifampin, midazolam, and simvastatin, as it can cause adverse effects or reduce efficacy.
  • Inform your doctor about all current medications, including herbal supplements.

£78.54
Lopimune Tablets
Lopimune (Lopinavir 200mg and Ritonavir 50mg Tablets) (Lopimune )

Lopimune (Lopinavir 200mg and Ritonavir 50mg Tablets)

Lopimune (Lopinavir 200mg and Ritonavir 50mg Tablets) contains two active ingredients Lopinavir and Ritonavir.  It is mainly used to treat people with human immunodeficiency virus (HIV) infection. You can buy Lopimune (Lopinavir 200mg and Ritonavir 50mg Tablets) online also.

This medication is an HIV-1 protease inhibitor which is used in combination with other antiretroviral agents for HIV-1 infection treatment in adults and paediatric patients 14 days and older.

 

Lopimune (Lopinavir 200mg and Ritonavir 50mg Tablets) used for?

Lopimune (Lopinavir 200mg and Ritonavir 50mg Tablets) are a fixed dose combination treatment for Human Immunodeficiency Virus (HIV) infection in adults over and children over 6 months. Lopimune (Lopinavir 200mg and Ritonavir 50mg Tablets) are used in combination with other medications that have a different mechanism of action to the components in Lopimune (Lopinavir 200mg and Ritonavir 50mg Tablets), and are used to treat patients with HIV infection who have either already received treatment with other medications for HIV or as first line therapy for treatment-inexperienced patients. HIV impairs the immune system by attacking specific immune cells called CD4+ cells that are involved in fighting infection and this can lead to opportunistic life-threatening infection (infections that would not normally be harmful); also if too many CD4+ cells are destroyed this can result in acquired immune deficiency syndrome (AIDS). Lopimune (Lopinavir 200mg and Ritonavir 50mg Tablets) prevent or slow down the ability of HIV to replicate and spread, which keeps the amount virus down to a low level and this results in an increase in CD4+ cell numbers, so that the immune system can recover, reducing the risk of disease progression.

 

Lopimune (Lopinavir 200mg and Ritonavir 50mg Tablets) work?

Lopimune (Lopinavir 200mg and Ritonavir 50mg Tablets) contain lopinavir and ritonavir, which are both inhibitors of HIV protease and are only effective against RNA viruses (retroviruses) like Human Immunodeficiency Virus (HIV). Retroviruses convert RNA to DNA, by the action of the viral-specific enzyme reverse transcriptase (RT). The viral DNA is then integrated into the DNA of infected immune cells so that the virus can replicate. Most of the antiviral activity of Lopimune (Lopinavir 200mg and Ritonavir 50mg Tablets) is due to lopinavir, which is a potent inhibitor of HIV protease, and prevents cleavage of the Gag-Pol polyprotein, an important protein in the development of active virus. The viral protease enzyme cleaves (breaks down) the Gag-Pol polyprotein during final stages of the replication cycle so that fully active mature virus can be released to infect new cells. Inhibition of protease cleavage by Lopimune (Lopinavir 200mg and Ritonavir 50mg Tablets) results in the production of immature, non-infectious viral particles. Ritonavir in Lopimune (Lopinavir 200mg and Ritonavir 50mg Tablets) is included in the combination not as a protease inhibitor but because it inhibits the CYP3A-mediated metabolism (breakdown in the liver) of lopinavir, thereby increasing the plasma levels of lopinavir so that lopinavir can be used at a lower dose. Lopimune (Lopinavir 200mg and Ritonavir 50mg Tablets) are used in combination with other retrovirals that have a different mechanism of action, like emtricitabine and tenofovir, both nucleoside reverse transcriptase inhibitor (NRTI) that work by blocking the action of RT, inhibiting viral replication. The combined action of lopinavir and ritonavir in Lopimune (Lopinavir 200mg and Ritonavir 50mg Tablets), in conjunction with other retroviral drugs, inhibits the production of active HIV so that the viral load (amount of virus) is reduced. Lopimune (Lopinavir 200mg and Ritonavir 50mg Tablets) slow down the replication of HIV within your body but does not kill the virus already incorporated in the CD4+ cells or prevent the spread of the infection to others.

 

Lopimune (Lopinavir 200mg and Ritonavir 50mg Tablets) Side Effects

  • The most common Lopimune (Lopinavir 200mg and Ritonavir 50mg Tablets) side effects occurring in 5% or more of the patients undergoing treatment with this medication were diarrhea, nausea, abdominal pain, asthenia, vomiting, headache, and dyspepsia.
  • The most commonly reported Generic Kaletra side effects of moderate severity that are thought to be drug related are: abdominal pain, abnormal stools (bowel movements), diarrhea, feeling tired, headache, and nausea. Children taking this medicine may sometimes get a skin rash.
  • Blood tests in patients taking this medicine may show possible liver problems. People with liver disease such as Hepatitis B and Hepatitis C who take this medicine may have worsening liver disease. Liver problems including death have occurred in patients taking this medicine. In studies, it is unclear if this medicine caused these liver problems because some patients had other illnesses or were taking other medicines.
  • Some patients taking this medicine can develop serious problems with their pancreas (pancreatitis), which may cause death. You have a higher chance of having pancreatitis if you have had it before. Tell your doctor if you have nausea, vomiting, or abdominal pain. These may be signs of pancreatitis.
  • Some patients have large increases in triglycerides and cholesterol. The long-term chance of getting complications such as heart attacks or stroke due to increases in triglycerides and cholesterol caused by protease inhibitors is not known at this time.
  • Diabetes and high blood sugar (hyperglycemia) occur in patients taking protease inhibitors such as this medicine. Some patients had diabetes before starting protease inhibitors, others did not. Some patients need changes in their diabetes medicine. Others needed new diabetes medicine.
  • Changes in body fat have been seen in some patients taking antiretroviral therapy. These changes may include increased amount of fat in the upper back and neck ("buffalo hump"), breast, and around the trunk. Loss of fat from the legs, arms and face may also happen. The cause and long term health effects of these conditions are not known at this time.
  • Some patients with hemophilia have increased bleeding with protease inhibitors. There have been other side effects in patients taking this medicine. However, these side effects may have been due to other medicines that patients were taking or to the illness itself. Some of these side effects can be serious. If you suspect that you took more than the prescribed dose of this medicine, contact your local poison control center or emergency room immediately. As with all prescription medicines, this medicine should be kept out of the reach of young children.

 

What medications interact with Lopimune (Lopinavir 200mg and Ritonavir 50mg Tablets)?

Always inform your physician about the drugs you are taking till date. Provide complete list of prescription or non prescription drugs and any other disease. This way, your physician will assist you with the list of medicine and other things that may interact with Lopimune (Lopinavir 200mg and Ritonavir 50mg Tablets).

 

Warnings & Precautions When Using Lopimune (Lopinavir 200mg and Ritonavir 50mg Tablets)

  • Do not take this medicine if you have had a serious allergic reaction to Lopinavir or Ritonavir (the active ingredients).
  • This medicine may be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment. It is not known whether this medicine passes into breast milk or if it could harm a nursing baby.
  • You should tell your doctor if you have liver problems or are infected with Hepatitis B or Hepatitis C.
  • Some people taking protease inhibitors develop new or more serious diabetes or high blood sugar. Be sure to tell your doctor if you have diabetes or an increase in thirst and/or frequent urination. Some people with hemophilia have had increased bleeding. It is not known whether the protease inhibitors caused these problems. Be sure to tell your doctor if you have hemophilia types A and B. Together with your doctor, you need to decide whether this medicine is right for you.
  • Do not take this medicine if you are taking certain other medicines. These could cause serious side effects that could cause death. Before you take this medicine, you must tell your doctor about all the medicines you are taking or are planning to take.
£121.37
Triomune
Triomune (Lamivudine 30mg, Stavudine 150mg and Nevirapine 200mg Tablets) (Triomune )

Triomune (Lamivudine 30mg, Stavudine 150mg and Nevirapine 200mg Tablets)

This drug has a generic name Stavudine, Lamivudine, Nevirapine which contains 30 Mg of Stavudine, 150mg of lamivudine and 200mg of nevirapine. It is considered as antiretroviral type of medication which is a fixed dose combination treatment in prevention of Human Immunodeficiency Virus (HIV). This medication can help in slow down the ability of HIV to replicate and spread. It allows the number of CD4+ cells to increase and to help the immune system to recover and reduce the risk of disease spread.  

 

Triomune (Lamivudine 30mg, Stavudine 150mg and Nevirapine 200mg Tablets) Uses :

Triomune (Lamivudine 30mg, Stavudine 150mg and Nevirapine 200mg Tablets) is an antiviral drug that prevents the human immunodeficiency virus (HIV) virus from multiplying in the body. This medication is used in the treatment of HIV/AIDS. Triomune (Lamivudine 30mg, Stavudine 150mg and Nevirapine 200mg Tablets)will however, not cure the body of HIV.

 

Triomune (Lamivudine 30mg, Stavudine 150mg and Nevirapine 200mg Tablets) work?

Triomune (Lamivudine 30mg, Stavudine 150mg and Nevirapine 200mg Tablets) contain a combination of 3 antiretroviral drugs stavudine, lamivudine and nevirapine, which are effective only against RNA viruses (retroviruses) like Human Immunodeficiency Virus (HIV). These three drugs each work by inhibiting the action of the viral-specific enzyme reverse transcriptase (RT) which is needed for the virus to be able to replicate. Retroviruses convert RNA to DNA, which is then integrated into the DNA of infected immune cells so that the virus can replicate. Nevirapine in Triomune (Lamivudine 30mg, Stavudine 150mg and Nevirapine 200mg Tablets) is a dipyridodiazepine derivative non-nucleoside reverse transcriptase inhibitor (NNRTI); nucleosides are the precursors to the building blocks of DNA and RNA. Nevirapine in Triomune (Lamivudine 30mg, Stavudine 150mg and Nevirapine 200mg Tablets) acts by binding to a specific site on the RT enzyme, the enzyme's active site known as the NNRTI pocket, disrupting the catalytic site of the enzyme, and blocking its action in a manner that is noncompetitive with nucleosides. Stavudine and lamivudine are both nucleoside analogue reverse transcriptase inhibitors (NRTI), which means that they block the action of RT by competing with one of the nucleosides needed to transcribe the viral RNA into DNA, becoming incorporated into the chain of newly synthesized viral DNA and preventing it from growing (chain termination). Stavudine is an analogue of thymidine and lamivudine is an analogue of cytidine. The combined action of the three antiiretroviral drugs in Triomune (Lamivudine 30mg, Stavudine 150mg and Nevirapine 200mg Tablets) prevents the integration of the virus into the DNA of the infected CD4+ immune cell by 2 different mechanisms, which inhibits the replication of HIV so that no more virus can be produced and this reduces the viral load (amount of virus). Triomune (Lamivudine 30mg, Stavudine 150mg and Nevirapine 200mg Tablets) slows down the replication of HIV within your body but does not kill the virus already incorporated in the CD4+ cells or prevent the spread of the infection to others.

 

Triomune (Lamivudine 30mg, Stavudine 150mg and Nevirapine 200mg Tablets) Dosage Information

All three drugs are generally recommended twice daily, permitting a fixed-dose combination to be formulated. With the availability of this combination formulation, patients may be better able to adhere to triple drug regimens, thereby enhancing compliance. Store the medicine at room temperature away from moisture. It is usually taken by the patients weighing less than 60 kg.

Triomune (Lamivudine 30mg, Stavudine 150mg and Nevirapine 200mg Tablets) can be taken with or without food but it should be swallowed with a full glass of water. Always consult the doctor for proper dosage and duration of the treatment because it will depend on patient’s condition and other conditions like weight and their response to therapy. This medication can help to control HIV but it cannot be used to cure the virus. 

 

Triomune (Lamivudine 30mg, Stavudine 150mg and Nevirapine 200mg Tablets) Side effects:

Tell your doctor if you feel any of the following side effects while taking this drug, even if you have had them before:

  • Symptoms of lactic acidosis like muscle pain/weakness
  • Headache
  • Joint pain
  • Increased blood sugar levels
  • Increase in bleeding ( in people with Haemophillia)
  • Fat gain or loss
  • Tiredness
  • Diarrhea
  • Seizures
  • Unexplained weight loss
  • Vision changes, etc.

Do not get alarmed by the list. You may /may not experience all of them. Tell your doctor immediately in the above situations.

 

Triomune (Lamivudine 30mg, Stavudine 150mg and Nevirapine 200mg Tablets) Warning:

Things to remember:

  • Take necessary precautions to avoid getting infected, such as not being near sick people
  • Also involve in protected sex if you are infected with HIV, to avoid its transmission
  • Avoid activities that can increase the risk of bleeding
  • Store this medication in a cool and dry place
  • Never start a new medication without consulting your doctor first
£46.01
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